The Macosko lab is seeking an exceptional, highly self-motivated postdoctoral fellow to lead a project analyzing single cell and spatial genomics data from patients with X-linked Dystonia Parkinsonism, a rare genetic neurological disorder. This work is an extension of our technology development efforts in single cell and spatial transcriptomics methods, which have culminated in a high-throughput pipeline for building high-quality datasets using these technologies on postmortem brain specimens. Using results from human genetics to inform our analyses of these new datasets, we hope to uncover the pathogenic mechanisms underlying this currently mysterious neurological disorder. The candidate will join a vibrant, multidisciplinary environment of computational biologists, software engineers, molecular neuroscientists, and technology developers. Candidates should have experience analyzing complex, high-dimensional genomics datasets. A background in neuroscience is not essential.