OUR TEAM: The Promega Chappelle Manufacturing Center team consists of innovative professionals with diverse skillsets who work together to achieve our goal of manufacturing high-quality components used in Promega's Life Science products and APIs to support cutting-edge therapeutic development. To achieve this goal, we build strong relationships, collaborate openly, and embrace the attitude of 'How can we do this the right way?' when facing challenges. We believe that to succeed as a team, we need to create a space for optimistic learning and shared belonging, leveraging each other's strengths and celebrating our differences. We are looking to build our team with members who share these values and are inspired to take on the new opportunities that inevitably await!

YOUR ROLE: This scientist is responsible for optimizing and scaling up chemical processes to ensure efficient and cost-effective production up to a 2000L scale. The role involves designing experiments, analyzing process data, and implementing improvements in synthetic routes and methodologies. The scientist collaborates with cross-functional teams to troubleshoot manufacturing issues, enhance yields, and ensure compliance with EHS standards.

YOUR EXPERIENCE: We are seeking a scientist with expertise in organic synthesis, analytical techniques, and process simulation tools. The ideal candidate will drive innovation in process design and contribute significantly to the development of high-quality products.

CORE DUTIES:

1. Design of processes for optimization and scale-up of a variety of projects.

2. Develop individual research plans for assigned projects. High level of expectation to meet deadlines of assigned projects.

3. Apply novel methods of experimentation to solve complex problems. Maintain high level of knowledge related to current developments in scientific field of expertise. Identify and attend relevant continuing educational seminars and short courses.

4. Perform all laboratory projects in accordance with established safety procedures in assigned laboratory or work area. Responsible for monitoring safety practices of assigned personnel.

5. Maintain accurate research documentation. Organize program results and prepare project status reports or presentations for the research team and business associates.

6. Conduct interpretive literature reviews for future project ideas. Present oral and written reports to outside scientific collaborators and/or business associates as directed by company leadership.

7. Identify, justify, and implement major processes improvements to existing chemistries and work collaboratively with Tech Transfer, Manufacturing, and Quality personnel to implement changes.

8. Assist and provide consultation in the transfer of the scaled-up processes into the manufacturing group.

9. Lead the development of manufacturing methods, including documentation.

10. Maintain a high level of familiarity with all processes and products manufactured within the plant.

11. Collaborate with Manufacturing and contribute creatively to current and prospective projects. Determine the business case to support new productions process and equipment.

12. Establish contacts with outside vendors for specialized services or materials.

13. Implement process development and engineering control practices within manufacturing. Bring high statistical capability to processes and test methods.

14. May conduct educational seminars within the department to advance technical and theoretical competence.

15. Understand the capabilities and limitations of various plant equipment and reactors. Ability to design new processes, or modify/scale-up current processes, that are appropriate for existing plant equipment. Ability to recognize various non-scalable conditions.

16. Demonstrates inclusion through their own words and actions and is accountable for a safe workspace. Acts with kindness, curiosity and respect for others.

17. Embracing and being open to incorporating Promega's 6 Emotional & Social Intelligence (ESI) core principles in daily work.

18. Understands and complies with ethical, legal and regulatory requirements applicable to our business.

KEY QUALIFICATIONS:

1. Ph.D. in Chemistry or Chemical Engineering and 3-6 years industrial experience or MS in Organic Chemistry with 8+ years industrial experience.

2. Experience in chemistry process development and scale-up of organic chemicals.

3. Demonstrated ability to recognize opportunities to implement process improvements related to safety, quality, reproducibility, environmental impact, productivity, and scalability.

4. Full understanding of state-of-the art process and analytical research technologies.

5. Shows good judgment about which creative ideas and suggestions will work and can facilitate effective and collaborative brainstorming.

6. Willingness to work on potent molecules.

7. Ability to work independently on complex assignments.

8. Strong safety mindset.

9. Outstanding critical thinking and troubleshooting skills.

10. Excellent written and verbal communication skills. Ability to interpret and communicate scientific results and to interact productively with scientists in the team.

11. Successful in implementing ideas and influencing people in a team environment. Recognized for organized, effective, and professional communication skills. Strong ability to independently resolve interpersonal conflicts.

12. Experience in successful collaboration with vendors to identify, purchase, install, and repair existing and new instruments and equipment.

PREFERRED QUALIFICATIONS:

1. Experience in crystallization, isolation and purification.

2. Experience in cGMP-compliant API development, scale-up, and tech transfer.

3. Facilitate collaborative efforts among key stakeholders across different functional areas.

PHYSICAL DEMANDS:

1. Ability to work at a laboratory bench for extended periods of time.

2. Ability to work with hazardous materials (e.g., chemicals) so as not to endanger oneself or others.

3. Ability to use computers in an interactive manner for extended periods of time.

4. Ability to work in a production environment around automated equipment.

5. Ability to use standard laboratory personal protective equipment (e.g., goggles, lab coat, protective gloves).

6. Ability to move objects weighing up to 50 lb. occasionally.

7. Ability to travel by car or airplane, for one or several days, to suppliers, equipment vendors, trade shows, etc.

At Promega, we value diversity and strive to create an inclusive workplace. We are proud to be an Equal Opportunity Employer, making employment decisions without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran status, disability, or any other protected class.